I have to admit that I am a big baby when it comes to pain. I have a very low tolerance for it. They prescribed pain medication for me, which I figured I would need. To this day, I have yet to use any of it. I took an Extra Strength Tylenol before I went to sleep in my recliner, just to help kinda relax me. That was pretty much it. In fact, the only sensations I really experienced was the itchiness as the folicles started to grow. The only real pain I have experienced during this whole process is that from kicking myself in the rear from not having this done before now! One other thing, if you do experience any pain, it will subside when you get that yearly survey, where they send you a picture of your hairline before. You will be in shock, and realize that it was ALL WORTHWHILE!